Iowa State University

Iowa State University

Protein-RNA Interface Database (PRIDB) v2.0

Dobbs and Honavar Laboratories

Query parameters:

Query string: tRNA synthetase
Interaction definition: Distance-based, 5.0Å cutoff
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Query Results:

Minimize 4ARC
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4ARC: 1 protein chains, 1 RNA chains
Complex Name: Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation
Resolution:2 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: LEUCINE--TRNA LIGASE
M Q E Q Y R P E E I E S K V Q L H W D E K R T F E V T E D E S K E K Y Y C L S M L P Y P S G R L H M G H V R N Y T I G D V I A R Y Q R M L G K N V L Q P I G W D A F G L P A E G A A V K N N T A P A P W T Y D N I A Y M K N Q L K M L G F G Y D W S R E L A T C T P E Y Y R W E Q K F F T E L Y K K G L V Y K K T S A V E I P Q W F I K I T A Y A D E L L N D L D K L D H W P D T V K T M Q R N W I G R S E G V E I T F N V N D Y D N T L T V Y T T R P D T F M G C T Y L A V A A G H P L A Q K A A E N N P E L A A F I D E K G V D T G F K A V H P L T G E E I P V W A A N F V L M E Y G T G A V M A V P G H D Q R D Y E F A S K Y G L N I K P V I L A A D G S E P D L S Q Q A L T E K G V L F N S G E F N G L D H E A A F N A I A D K L T A M G V G E R K V N Y R L R D W G V S R Q R Y W G A P I P M V T L E D G T V M P T P D D Q L P V I L P E D V V M D G I T S P I K A D P E W A K T T V N G M P A L R E T D T F D T F M E S S W Y Y A R Y T C P Q Y K E G M L D S E A A N Y W L P V D I Y I G G I E H A I M H L L Y F R F F H K L M R D A G M V N S D E P A K Q L L C Q G M V L A D A F Y Y V G E N G E R N W V S P V D A I V E R D E K G R I V K A K D A A G H E L V Y T G M S K M S K S K N N G I D P Q V M V E R Y G A D T V R L F M M F A S P A D M T L E W Q E S G V E G A N R F L K R V W K L V Y E H T A K G D V A A L N V D A L T E N Q K A L R R D V H K T I A K V T D D I G R R Q T F N T A I A A I M E L M N K L A K A P T D G E Q D R A L M Q E A L L A V V R M L N P F T P H I C F T L W Q E L K G E G D I D N A P W P V A D E K A M V E D S T L V V V Q V N G K V R A K I T V P V D A T E E Q V R E R A G Q E H L V A K Y L D G V T V R K V I Y V P G K L L N L V V L
Chain: B, Molecule: TRNA-LEU5 (UAA ISOACCEPTOR)
G G A U G G U G G A A U C G G U A G A C A C A A G G G A U C C C U C G G C G U U C G C G C U G U G C G G G U U C A A G U C C C G C U C C C C A

Minimize 4ARI
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4ARI: 1 protein chains, 1 RNA chains
Complex Name: Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation
Resolution:2.08 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: LEUCINE--TRNA LIGASE
H M Q E Q Y R P E E I E S K V Q L H W D E K R T F E V T E D E S K E K Y Y C L S M L P Y P S G R L H M G H V R N Y T I G D V I A R Y Q R M L G K N V L Q P I G W D A F G L P A E G A A V K N N T A P A P W T Y D N I A Y M K N Q L K M L G F G Y D W S R E L A T C T P E Y Y R W E Q K F F T E L Y K K G L V Y K K T S A V E I P Q W F I K I T A Y A D E L L N D L D K L D H W P D T V K T M Q R N W I G R S E G V E I T F N V N D Y D N T L T V Y T T R P D T F M G C T Y L A V A A G H P L A Q K A A E N N P E L A A F I D E C R N T E K K G V D T G F K A V H P L T G E E I P V W A A N F V L M E Y G T G A V M A V P G H D Q R D Y E F A S K Y G L N I K P V I L A A D G S E P D L S Q Q A L T E K G V L F N S G E F N G L D H E A A F N A I A D K L T A M G V G E R K V N Y R L R D W G V S R Q R Y W G A P I P M V T L E D G T V M P T P D D Q L P V I L P E D V V M D G I T S P I K A D P E W A K T T V N G M P A L R E T D T F D T F M E S S W Y Y A R Y T C P Q Y K E G M L D S E A A N Y W L P V D I Y I G G I E H A I M H L L Y F R F F H K L M R D A G M V N S D E P A K Q L L C Q G M V L A D A F Y Y V G E N G E R N W V S P V D A I V E R D E K G R I V K A K D A A G H E L V Y T G M S K M S K S K N N G I D P Q V M V E R Y G A D T V R L F M M F A S P A D M T L E W Q E S G V E G A N R F L K R V W K L V Y E H T A K G D V A A L N V D A L T E N Q K A L R R D V H K T I A K V T D D I G R R Q T F N T A I A A I M E L M N K L A K A P T D G E Q D R A L M Q E A L L A V V R M L N P F T P H I C F T L W Q E L K G E G D I D N A P W P V A D E K A M V E D S T L V V V Q V N G K V R A K I T V P V D A T E E Q V R E R A G Q E H L V A K Y L D G V T V R K V I Y V P G K L L N L V V G
Chain: B, Molecule: TRNA-LEU5 (UAA ISOACEPTOR)
G C C C G G A U G G U G G A A U C G G U A G A C A C A A G G G A U C C C U C G G C G U U C G C G C U G U G C G G G U U C A A G U C C C G C U C C G G G U A C C

Minimize 4AS1
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4AS1: 1 protein chains, 1 RNA chains
Complex Name: Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation
Resolution:2.02 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: LEUCINE--TRNA LIGASE
M Q E Q Y R P E E I E S K V Q L H W D E K R T F E V T E D E S K E K Y Y C L S M L P Y P S G R L H M G H V R N Y T I G D V I A R Y Q R M L G K N V L Q P I G W D A F G L P A E G A A V K N N T A P A P W T Y D N I A Y M K N Q L K M L G F G Y D W S R E L A T C T P E Y Y R W E Q K F F T E L Y K K G L V Y K K T S A V N W E R K E I P Q W F I K I T A Y A D E L L N D L D K L D H W P D T V K T M Q R N W I G R S E G V E I T F N V N D Y D N T L T V Y T T R P D T F M G C T Y L A V A A G H P L A Q K A A E N N P E L A A F I D E C R N T M E K K G V D T G F K A V H P L T G E E I P V W A A N F V L M E Y G T G A V M A V P G H D Q R D Y E F A S K Y G L N I K P V I L A A D G S E P D L S Q Q A L T E K G V L F N S G E F N G L D H E A A F N A I A D K L T A M G V G E R K V N Y R L R D W G V S R Q R Y W G A P I P M V T L E D G T V M P T P D D Q L P V I L P E D V V M D G I T S P I K A D P E W A K T T V N G M P A L R E T D T F D T F M E S S W Y Y A R Y T C P Q Y K E G M L D S E A A N Y W L P V D I Y I G G I E H A I M H L L Y F R F F H K L M R D A G M V N S D E P A K Q L L C Q G M V L A D A F Y Y V G E N G E R N W V S P V D A I V E R D E K G R I V K A K D A A G H E L V Y T G M S K M S K S K N N G I D P Q V M V E R Y G A D T V R L F M M F A S P A D M T L E W Q E S G V E G A N R F L K R V W K L V Y E H T A K G D V A A L N V D A L T E N Q K A L R R D V H K T I A K V T D D I G R R Q T F N T A I A A I M E L M N K L A K A P T D G E Q D R A L M Q E A L L A V V R M L N P F T P H I C F T L W Q E L K G E G D I D N A P W P V A D E K A M V E D S T L V V V Q V N G K V R A K I T V P V D A T E E Q V R E R A G Q E H L V V I Y V P G K L L N L
Chain: B, Molecule: TRNA-LEU5 (UAA ISOACEPTOR)
G C C C G G A U G G U G G A A U C G G U A G A C A C A A G G G A A A A U C C C U C G G C G U U C G C G C U G U G C G G G U U C A A G U C C C G C U C C G G G U A C C

Minimize 4JXX
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4JXX: 1 protein chains, 1 RNA chains
Complex Name: Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG) and ATP from novel cryostabilization conditions
Resolution:2.3 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: Glutamine--tRNA ligase
P T N F I R Q I I D E D L A S G K H T T V H T R F P P E P N G Y L H I G H A K S I C L N F G I A Q D Y K G Q C N L R F D D T N P V K E D I E Y V E S I K N D V E W L G F H W S G N V R Y S S D Y F D Q L H A Y A I E L I N K G L A Y V D E L T P E Q I R E Y R G T L T Q P G K N S P Y R D R S V E E N L A L F E K M R A G G F E E G K A C L R A K I D M A S P F I V M R D P V L Y R I K F A E H H Q T G N K W C I Y P M Y D F T H C I S D A L E G I T H S L C T L E F Q D N R R L Y D W V L D N I T I P V H P R Q Y E F S R L N L E Y T V M S K R K L N L L V T D K H V E G W D D P R M P T I S G L R R R G Y T A A S I R E F C K R I G V T K Q D N T I E M A S L E S C I R E D L N E N A P R A M A V I D P V K L V I E N Y Q G E G E M V T M P N H P N K P E M G S R Q V P F S G E I W I D R A D F R E E A N K Q Y K R L V L G K E V R L R N A Y V I K A E R V E K D A E G N I T T I F C T Y D A D T L S R K V K G V I H W V S A A H A L P V E I R L Y D R L F S V P N P G A A D D F L S V I N P E S L V I K Q G F A E P S L K D A V A G K A F Q F E R E G Y F C L D S R H S T A E K P V F N R T V G L R D T W
Chain: B, Molecule: RNA (71-MER)
G G G G U A U C G C C A A G C G G U A A G G C A C C G G A U U C U G A U U C C G G C C C G A G G U U C G A A U C C U C G U A C C C C A G C C A

Minimize 4JXZ
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4JXZ: 1 protein chains, 1 RNA chains
Complex Name: Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon
Resolution:2.4 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: Glutamine--tRNA ligase
P T N F I R Q I I D E D L A S G K H T T V H T R F P P E P N G Y L H I G H A K S I C L N F G I A Q D Y K G Q C N L R F D D T N P V K E D I E Y V E S I K N D V E W L G F H W S G N V R Y S S D Y F D Q L H A Y A I E L I N K G L A Y V D E L T P E Q I R E Y R G T L T Q P G K N S P Y R D R S V E E N L A L F E K M R A G G F E E G K A C L R A K I D M A S P F I V M R D P V L Y R I K F A E H H Q T G N K W C I Y P M Y D F T H C I S D A L E G I T H S L C T L E F Q D N R R L Y D W V L D N I T I P V H P R Q Y E F S R L N L E Y T V M S K R K L N L L V T D K H V E G W D D P R M P T I S G L R R R G Y T A A S I R E F C K R I G V T K Q D N T I E M A S L E S C I R E D L N E N A P R A M A V I D P V K L V I E N Y Q G E G E M V T M P N H P N K P E M G S R Q V P F S G E I W I D R A D F R E E A N K Q Y K R L V L G K E V R L R N A Y V I K A E R V E K D A E G N I T T I F C T Y D A D T L S K G R K V K G V I H W V S A A H A L P V E I R L Y D R L F S V P N P G A A D D F L S V I N P E S L V I K Q G F A E P S L K D A V A G K A F Q F E R E G Y F C L D S R H S T A E K P V F N R T V G L R D T W
Chain: B, Molecule: RNA (71-MER)
G G G G U A U C G C C A A G C G G U A A G G C A C C G G U U U U U G A U A C C G G C C G C A G G U U C G A A U C C U G C U A C C C C A G C C A

Minimize 4JYZ
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4JYZ: 1 protein chains, 1 RNA chains
Complex Name: Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base
Resolution:2.5 Å
Solving Method:X-RAY DIFFRACTION

Interactions:


Prosite -

Chain: A, Molecule: Glutamine--tRNA ligase
P T N F I R Q I I D E D L A S G K H T T V H T R F P P E P N G Y L H I G H A K S I C L N F G I A Q D Y K G Q C N L R F D D T N P V K E D I E Y V E S I K N D V E W L G F H W S G N V R Y S S D Y F D Q L H A Y A I E L I N K G L A Y V D E L T P E Q I R E Y R G T L T Q P G K N S P Y R D R S V E E N L A L F E K M R A G G F E E G K A C L R A K I D M A S P F I V M R D P V L Y R I K F A E H H Q T G N K W C I Y P M Y D F T H C I S D A L E G I T H S L C T L E F Q D N R R L Y D W V L D N I T I P V H P R Q Y E F S R L N L E Y T V M S K R K L N L L V T D K H V E G W D D P R M P T I S G L R R R G Y T A A S I R E F C K R I G V T K Q D N T I E M A S L E S C I R E D L N E N A P R A M A V I D P V K L V I E N Y Q G E G E M V T M P N H P N K P E M G S R Q V P F S G E I W I D R A D F R E E A N K Q Y K R L V L G K E V R L R N A Y V I K A E R V E K D A E G N I T T I F C T Y D A D T L S K D P A D G R K V K G V I H W V S A A H A L P V E I R L Y D R L F S V P N P G A A D D F L S V I N P E S L V I K Q G F A E P S L K D A V A G K A F Q F E R E G Y F C L D S R H S T A E K P V F N R T V G L R D T W
Chain: B, Molecule: RNA (72-MER)
G G G G U A 4SU C G C C A A G C OMG G H2U A A G G C A C C G G U OMU U U G 2MA PSU A C C G G C A C G C A G G 5MU PSU C G A A U C C U G C U A C C C C A G C C A


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Showing results 71 to 76 of 76